Plasma Activity of Muscle Enzymes: Quantification of Skeletal Muscle Damage and Relationship with Metabolic Variables
| Autor: | G. M. Willems, M. P. E. Janssen, Harm Kuipers, G. M. E. Janssen, Ronald J. M. M. Does, P. Geurten |
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| Rok vydání: | 1989 |
| Předmět: |
Adult
Male medicine.medical_specialty Physical Exertion Physical Therapy Sports Therapy and Rehabilitation Physical exercise Muscle damage Running Endurance training Internal medicine Blood plasma medicine Humans Orthopedics and Sports Medicine Aspartate Aminotransferases Treadmill Creatine Kinase chemistry.chemical_classification biology business.industry Muscles Half-life Alanine Transaminase Middle Aged Adaptation Physiological Enzyme Endocrinology chemistry Evaluation Studies as Topic Physical Endurance biology.protein Female Creatine kinase business Half-Life |
| Zdroj: | International Journal of Sports Medicine. 10:S160-S168 |
| ISSN: | 1439-3964 0172-4622 |
| DOI: | 10.1055/s-2007-1024966 |
| Popis: | One hundred fourteen sedentary volunteers (34 +/- 8 years) took part in an endurance training study to be completed after 18-20 months with a marathon. Ultimately, 60 males and 18 females achieved that goal. The training program, carefully supervised, was divided into three periods with a maximum of 45-, 70-, and 110-km week training volume and concluded with a performance race of 15, 25, and 42.2 km, respectively. Three days before and 3 and 5 days after each race, 35 subjects were selected to perform a progressive treadmill test and the remaining subjects participated in field tests of 400 and 1000 m. A significant decrease in half-life time of CK enzyme plasma activity after running long distances in the course of the study from 20 h to 13 h was observed. Based on plasma enzyme activity and supposing that the total enzyme content left the muscle fiber, the estimated amount of muscle damage was found to be small. A gender difference in plasma enzyme activity increase (females demonstrated a lower increase) occurred only after the marathon. |
| Databáze: | OpenAIRE |
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