Maximal Expiratory and Inspiratory Flow-Volume Curves in Parkinson's Disease
| Autor: | F. G. A. v. d. Meché, J. M. Bogaard, A. Hovestadt, J. Stigt, J. D. Meerwaldt |
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| Rok vydání: | 1989 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Parkinson's disease Maximal expiratory flow-volume curves Vital Capacity Peak Expiratory Flow Rate Inspiratory flow Internal medicine Pressure medicine Humans Lung volumes Peak flow meter Maximal Expiratory Flow-Volume Curves measurement_unit Mouth business.industry Total Lung Capacity Parkinson Disease Forced Expiratory Flow Rates Airway obstruction medicine.disease Surgery Airway Obstruction Residual Volume Volume (thermodynamics) measurement_unit.measuring_instrument Cardiology Pulmonary Ventilation business |
| Zdroj: | American Review of Respiratory Disease. 139:610-614 |
| ISSN: | 0003-0805 |
| DOI: | 10.1164/ajrccm/139.3.610 |
| Popis: | In order to investigate the type and degree of upper airway obstruction (UAO) in a group of patients with Parkinson's disease in different stages of the disease, we obtained maximal expiratory and inspiratory flow-volume (MEFV and MIFV) curves and maximal static mouth pressures. The clinical disability was indicated by a Hoehn-Yahr (H-Y) scale, ranging from III to V, and a more continuous Northwestern University Disability Scale (NUDS), ranging from zero to 50. Twelve patients were in H-Y Group III, and eleven and eight were in Groups IV and V, respectively. The pattern of the flow-volume curves was classified as either normal, or with superimposed regular or irregular oscillations (A), or with rounded-off and delayed expiratory peak appearance (B). Mean MEFV curves in Groups III and IV were not appreciably different from reference. In Group V, the mean curve showed a lower peak expiratory flow (PEF) and a more convex tail. Only the effort-dependent variables PEF, peak inspiratory flow (PIF), and maximal mouth pressures at RV and TLC (PmTLC and PmRV) appeared to be significantly correlated with the NUDS index and decreased with increasing clinical disability. The mean values of those variables were also significantly different between the H-Y groups. The number of normal curves decreased from H-Y Group III to Group V. The contribution of A and B curves was relatively equal in the groups, with only a small number of A curves.(ABSTRACT TRUNCATED AT 250 WORDS) |
| Databáze: | OpenAIRE |
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