Clinical Evolution of Patients Using Ventricular Assist Devices as a Bridge for Transplantation
| Autor: | G.G. de Vasconcelos, Maria Gyslane Vasconcelos Sobral, larissa pinheiro de souza, Raquel Sampaio Florêncio, J.D. de Souza Neto, Virna Ribeiro Feitosa Cestari, Vera Lúcia Mendes de Paula Pessoa, A. Braga, Thereza Maria Magalhães Moreira |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Waiting Lists medicine.medical_treatment 030232 urology & nephrology 030204 cardiovascular system & hematology Hematocrit 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Odds Ratio Humans Cardiopulmonary disease Aged Retrospective Studies Heart transplantation Heart Failure Transplantation medicine.diagnostic_test business.industry Retrospective cohort study Odds ratio Middle Aged Treatment Outcome Ventricular assist device Heart Transplantation Surgery Female Heart-Assist Devices business Brazil Partial thromboplastin time |
| Zdroj: | Transplantation proceedings. 50(3) |
| ISSN: | 1873-2623 |
| Popis: | OBJECTIVE To evaluate the clinical evolution of patients with implantation of ventricular assist device (VAD) and identify the intervening factors for death. METHODS This analytical, retrospective study was carried out in a public reference hospital in cardiopulmonary diseases located in northeastern Brazil. The study population encompassed the medical records of 16 patients who underwent VAD implantation. Data collection took place from January to August 2016, through the consultation of medical records. Descriptive analysis, odds ratio, and the Fisher's Exact, Wilcoxon, Friedman and t-tests were used to analyze the data. RESULTS All patients experienced complications during the use of the device, with bleeding being the main cause (11 [68.8%]). There was a significant decrease in noradrenaline (P = .025), milrinone (Primacor; P = .007), and dobutamine (P = .046) flow rates with the clinical evolution of patients. Regarding hematologic parameters, the use of VAD promoted a significant improvement in hemoglobin (P < .001), hematocrit (P = .003), activated partial thromboplastin time (P = .013), and fibrinogen (P = .049) values at the 3 time points analyzed. Regarding the clinical outcome of the patients, the majority (10 [62.5%]) underwent cardiac transplantation. CONCLUSIONS This study allowed for better knowledge of the clinical evolution of patients with VAD implantation, highlighting the benefits of this type of device as a bridge for heart transplantation. |
| Databáze: | OpenAIRE |
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