Reacquisition of Specific Proteins Confers Virulence in Mycoplasma pneumoniae
| Autor: | D K Leith, Joel B. Baseman, Duncan C. Krause |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Pathogenic Mechanisms
Mycoplasma pneumoniae Immunology Mutant Virulence Biology medicine.disease_cause Microbiology Bacterial Proteins Cricetinae medicine Homologous chromosome Animals Hemadsorption Lung Mutation Mesocricetus Adhesiveness biology.organism_classification Virology Attachment organelle Infectious Diseases Respiratory epithelium Parasitology Peptides |
| Zdroj: | Infection and Immunity. 39:830-836 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.39.2.830-836.1983 |
| Popis: | Hemadsorbing revertants were isolated from spontaneous hemadsorption-negative, avirulent mutants of Mycoplasma pneumoniae. The revertants simultaneously reacquired specific proteins absent in their homologous mutants, along with neuraminidase-sensitive adherence to the respiratory epithelium and virulence. Peptide mapping and immunological analysis indicated no precursor-product relationships among certain of these proteins. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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