Surveillance of Populations at Risk of Cholangiocarcinoma Development in Rural Communities of Thailand Using the Korat-CCA Verbal Screening Test

Autor: Natthawut Kaewpitoon, Tanida Phatisena, Sukanya Ponphimai, Jun Norkaew, Natnapa Padchasuwan, Ryan A Loyd, Wasugree Chavengkun, Inchat Sukkasam, Likit Matrakool, Sukij Panpimanmas, Poowadol Polsripradist, Taweesak Tongtawee, Porntip Kompor, Jirawoot Kujapun, Thawatchai Eaksunti, Apinya Joosiri, Soraya J Kaewpitoon, Parichart Wakkhuwattapong, Ratana Rujirakul
Rok vydání: 2016
Předmět:
Male
Rural Population
0301 basic medicine
Cancer Research
Epidemiology
Cross-sectional study
Opisthorchiasis
Gastroenterology
Cholangiocarcinoma
0302 clinical medicine
Risk Factors
Mass Screening
Medicine
education.field_of_study
Gallstones
Middle Aged
Prognosis
Thailand
Praziquantel
Oncology
Population Surveillance
030220 oncology & carcinogenesis
cardiovascular system
Female
medicine.drug
Adult
medicine.medical_specialty
Screening test
Population
information science
03 medical and health sciences
Cronbach's alpha
Internal medicine
Environmental health
parasitic diseases
Animals
Humans
cardiovascular diseases
education
Mass screening
Verbal Behavior
business.industry
Opisthorchis
fungi
Public Health
Environmental and Occupational Health
medicine.disease
Bile Ducts
Intrahepatic
Cross-Sectional Studies
030104 developmental biology
Bile Duct Neoplasms
business
Follow-Up Studies
Zdroj: Asian Pacific Journal of Cancer Prevention. 17:2205-2209
ISSN: 1513-7368
DOI: 10.7314/apjcp.2016.17.4.2205
Popis: Cholangiocarcinoma (CCA) is a serious problem in Thailand, particularly in the northeastern region. Active surveillance in rural communities with an appropriat low-cost screening tool is required to facilitate early detection. Therefore, this study aimed to investigate the population at risk of CCA in Bua Yai district, Nakhon Ratchasima province, Northeastern Thailand using the Korat-CCA verbal screening test (KCVST) during June to October 2015. Reliability of KCVST demonstrated a Cronbach alpha coefficient=0.75 Stepwise-multiple regression showed that alcohol consumption was important for CCA screened, followed by agriculture and pesticide use, under-cooked cyprinoid fish consumption, praziquantel use, naïve northeastern people, opisthorchiasis, family relatives with CCA, and cholangitis or cholecystitis or gallstones, respectively. Population at risk for CCA was classified to low risk (63.4%), moderate risk (33.7%), and high risk (1.32%) for CCA. When CCA was screened using ultrasonography, 4 of 32 high risk participants had an abnormal biliary tract with dilated bile ducts. This study indicates that KCVST is a potential useful too which decrease the cost of large scale CCA screening.
Databáze: OpenAIRE
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