ETHNICITY AND BREAST CANCER CHARACTERISTICS IN KENYA
| Autor: | Zahir Moloo, Maya Palakal, Gretchen L. Gierach, Innocent Abayo, Costa Mariwa, Andrew Gachii, Abdihakim Mohammed, Rajendra Chauhan, Samuel M. Gakinya, Elizabeth B. Mwachiro, Patricia Okiro, Peter Bird, Ancent Nzioka, Mansoor N. Saleh, Joseph Karanu, Shaoqi Fan, Shahin Sayed, Robert Nyagah, Sanford M. Dawsey, Omar Sherman, Tilahun Nigatu Haregu, Betty Bonass, Shukri F. Mohamed, Ronald Wasike, Dan Omondi Raburu, James Obondi Otieno, JW Githaiga, Maeve Mullooly, Raymond Oigara, Irene Muramba, Satya Prasad, Mustafa Mussajee, Catherine Kyobutungi, Richard Njoroge, Asim Jamal Shaikh, Faith Wambui Njoroge, Sudhir Vinayak |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Adult Cancer Research Younger age Receptor ErbB-2 Ethnic group Breast Neoplasms Overweight Article First birth 03 medical and health sciences 0302 clinical medicine Breast cancer Surveys and Questionnaires medicine Ethnicity Humans Pathological Africa South of the Sahara Aged Traditional medicine business.industry Middle Aged Reproductive Factors medicine.disease Kenya Menopause 030104 developmental biology Oncology 030220 oncology & carcinogenesis Female medicine.symptom business Demography |
| Popis: | There are no published data from specific regions of sub-Saharan Africa describing the clinical and pathological characteristics and molecular subtypes of invasive breast cancer by ethnic group. The purpose of this study was to investigate these characteristics among the three major ethno-cultural groupings in Kenya. The study included women with pathologically confirmed breast cancer diagnosed between March 2012 and May 2015 at 11 hospitals throughout Kenya. Sociodemographic, clinical, and reproductive data were collected by questionnaire, and pathology review and immunohistochemistry were performed centrally. The 846 cases included 661 Bantus (78.1%), 143 Nilotes (16.9%), 19 Cushites (2.3%), and 23 patients of mixed ethnicity (2.7%). In analyses comparing the two major ethnic groups, Bantus were more educated, more overweight, had an older age at first birth, and had a younger age at menopause than Nilotes (p |
| Databáze: | OpenAIRE |
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