Acid and Gastrin Levels Following Pyloric-Preserving Pancreaticoduodenectomy

Autor: Nathan W. Pearlman, Louis M. Fink, Arnold L. Schultz, Dennis J. Ahnen, Gregory V. Stiegmann
Rok vydání: 1986
Předmět:
Zdroj: Archives of Surgery. 121:661
ISSN: 0004-0010
Popis: • Acid and gastrin production after pyloric-preserving pancreaticoduodenectomy was evaluated in six patients. Five patients had low-normal basal and stimulated acid output; the sixth patient was achlorhydric. Fasting gastrin levels were less than 90 to 105 pg/mL (normal range) in five patients, three of whom had stimulated gastrin levels that remained below this range. Two patients had stimulated gastrin levels of 510 pg/mL and 205 pg/mL, respectively, within 15 minutes of eating; however, both levels returned to normal by 120 minutes' time. The sixth patient had mildly elevated fasting (105 pg/mL) and stimulated gastrin levels (160 to 200 pg/mL) throughout the test period. The results suggest that pyloric-preserving pancreaticoduodenectomy does not lead to either gastric hyperacidity or persistent hypergastrinemia. ( Arch Surg 1986;121:661-664)
Databáze: OpenAIRE