Epidemiology and clinical impact of infection in patients awaiting heart transplantation
| Autor: | Julián Torre-Cisneros, Jose M. Arizón, Elisa Vidal, Antonio Rivero, Marcelino González-Padilla, Miguel Montejo, Carmen Segura, Juan José Castón |
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| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty medicine.medical_treatment Waiting list Comorbidity Communicable Diseases Risk Factors Internal medicine Epidemiology medicine Humans Mortality Heart transplantation Respiratory tract infections business.industry General Medicine Middle Aged medicine.disease Surgery Transplantation Patient Outcome Assessment Diarrhea Infectious Diseases Bacteremia Bronchitis Heart Transplantation Female medicine.symptom business Infection Follow-Up Studies |
| Zdroj: | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 17(9) |
| ISSN: | 1878-3511 |
| Popis: | Summary Objectives The aim of this study was to determine the epidemiology and clinical impact of infections in patients awaiting heart transplantation. Methods We evaluated all patients considered for a heart transplant in our center over a period of 18 months over a period of 18 months from 2007 to 2009. The patients were followed up for 8 months or until death, transplant, or loss to follow-up. Results Ninety patients were included in the study. During follow-up, 25 infections were recorded in 22 heart transplant candidates (24.4%). Respiratory infections were the most frequent infection (12 bronchitis; 48.0%), followed by skin and soft tissue infections (four infections; 16.0%), intra-abdominal infections (four infectious diarrhea; 16.0%), bacteremia (three infections; 12.0%), and urinary tract infections (two infections; 2.0%). Age, comorbidity, sex, and diabetes were not found to be risk factors for infection. Twenty-four patients (26.7%) were transplanted during follow-up. Infection before transplantation was not associated with an increased risk of mortality or a higher rate of infection in the immediate post-transplant period. Conclusions Infections are common in heart transplant candidates, affecting almost 25% of them. Respiratory tract infections are the most frequent type of infection. However, they are not associated with increased mortality in the immediate post-transplant period. |
| Databáze: | OpenAIRE |
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