Longitudinal alteration of cortical thickness and volume in high-impact sports

Autor: Michael Zeineh, Lex A. Mitchell, Phil DiGiacomo, Gerald A. Grant, Paymon Rezaii, Nicole Mouchawar, Carolyn Akers, Jarrett Rosenberg, Emily L. Dennis, David B. Camarillo, Brian Boldt, Huy M. Do, Sohrab Sami, Wei Bian, Brian D. Mills, Jaime R. Lopez, David B. Douglas, Max Wintermark, Mansi B. Parekh, Sherveen N. Parivash, Eugene Wilson, Maged Goubran
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Adolescent
Injury control
Cortical thickness and volume
Cognitive Neuroscience
Football
Poison control
Structural brain development
Functional Laterality
050105 experimental psychology
lcsh:RC321-571
Cohort Studies
Young Adult
03 medical and health sciences
0302 clinical medicine
Physical medicine and rehabilitation
Humans
Medicine
0501 psychology and cognitive sciences
College football
Longitudinal Studies
Prospective Studies
Gray Matter
Prospective cohort study
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
Brain Concussion
Cerebral Cortex
biology
business.industry
Athletes
05 social sciences
Brain
biology.organism_classification
Magnetic Resonance Imaging
Volleyball
Neurology
High-impact sports
Cohort
business
Structural imaging
030217 neurology & neurosurgery
Zdroj: NeuroImage, Vol 217, Iss, Pp 116864-(2020)
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2020.116864
Popis: Collegiate football athletes are subject to repeated head impacts. The purpose of this study was to determine whether this exposure can lead to changes in brain structure. This prospective cohort study was conducted with up to 4 years of follow-up on 63 football (high-impact) and 34 volleyball (control) male collegiate athletes with a total of 315 MRI scans (after exclusions: football n ​= ​50, volleyball n ​= ​24, total scans ​= ​273) using high-resolution structural imaging. Volumetric and cortical thickness estimates were derived using FreeSurfer 5.3’s longitudinal pipeline. A linear mixed-effects model assessed the effect of group (football vs. volleyball), time from baseline MRI, and the interaction between group and time. We confirmed an expected developmental decrement in cortical thickness and volume in our cohort (p ​
Databáze: OpenAIRE
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