Genetics, epidemiology, and clinical manifestations of multidrug-resistant Acinetobacter baumannii
| Autor: | Payman Nasr |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Microbiology (medical)
Acinetobacter baumannii medicine.medical_specialty medicine.drug_class Antibiotics 030501 epidemiology 03 medical and health sciences Antimicrobial Stewardship Mice Bacterial Proteins Drug Resistance Multiple Bacterial Epidemiology medicine Infection control Animals Humans Intensive care medicine 0303 health sciences Cross Infection Infection Control biology 030306 microbiology business.industry Incidence (epidemiology) Incidence Vaccination General Medicine Length of Stay Antimicrobial biology.organism_classification Hospitals Anti-Bacterial Agents Multiple drug resistance Infectious Diseases Mutation 0305 other medical science Multidrug resistant Acinetobacter baumannii business Acinetobacter Infections |
| Zdroj: | The Journal of hospital infection. 104(1) |
| ISSN: | 1532-2939 |
| Popis: | Summary Acinetobacter baumannii infections have become an emerging health concern in hospitals across the world and are often associated with nosocomial infections with poorer clinical outcomes in patients with prolonged hospital stay. Management of infections involves prompt identification of the infecting strain, isolating the source of infection, and proper choice of antibiotic regimen. However, resistance to first-line antimicrobial drugs, combined with a lack of equally effective alternatives, complicates the treatment of multidrug-resistant A. baumannii. Presently, multidrug-resistant A. baumannii is a serious health concern in hospitals and long-term care facilities and requires immediate and sustained prevention efforts to control the rate of incidence. This review describes trends in epidemiology, genetic markers, and other factors that influence the incidence of multidrug-resistant A. baumannii. Current and emerging treatments as well as infection control strategies are discussed. |
| Databáze: | OpenAIRE |
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