Potassium-stimulated, calcium-dependent release of [3H]GABA from neuron- and glia-enriched cultures of cells dissociated from rat cerebellum
Autor: | Gary R. Dutton, Richard Beale, Brian Pearce, D. Neil Currie |
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Rok vydání: | 1981 |
Předmět: |
Cerebellum
Potassium Population chemistry.chemical_element Biology Synaptic Transmission gamma-Aminobutyric acid Culture Techniques medicine Animals education Molecular Biology gamma-Aminobutyric Acid Neurons education.field_of_study General Neuroscience Depolarization Cell biology Rats medicine.anatomical_structure nervous system chemistry Biochemistry Cell culture Neuroglia Calcium Neurology (clinical) Neuron Developmental Biology medicine.drug |
Zdroj: | Brain research. 206(2) |
ISSN: | 0006-8993 |
Popis: | The release of [3H]GABA from cultures of cells dissociated from the rat cerebellum was investigated. The culture system contained a population of neurons (stellate and basket cells) which were capable of accumulating [3H]GABA and releasing it in a calcium-dependent manner in response to 50 mM potassium. In addition, the release of [3H]GABA for cultured astrocytes was found to be insensitive to potassium depolarization. |
Databáze: | OpenAIRE |
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