Cobalt-Catalyzed Hydrofluorination of Unactivated Olefins: A Radical Approach of Fluorine Transfer
| Autor: | Eriko Nishi, Kou Hiroya, Hiroki Shigehisa, Mayu Fujisawa |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
inorganic chemicals
Free Radicals Hydrocarbons Fluorinated Molecular Structure Organic Chemistry Markovnikov's rule chemistry.chemical_element Cobalt Fluorine Alkenes Biochemistry Catalysis Cobalt catalyst chemistry.chemical_compound chemistry Functional group Organometallic Compounds Organic chemistry Physical and Theoretical Chemistry Selectivity |
| Zdroj: | Organic Letters. 15:5158-5161 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/ol402696h |
| Popis: | Catalytic hydrofluorination of olefins using a cobalt catalyst was developed. The exclusive Markovnikov selectivity, functional group tolerance, and scalability of this reaction make it an attractive protocol for the hydrofluorination of olefins. A preliminary mechanistic experiment showed the involvement of a radical intermediate. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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