Calcium intake: good for the bones but bad for the heart? An analysis of clinical studies

Autor: Priscilla Damião Araújo Lima, Lívia Paiva Vardiero, Elisa Fernandes de Melo, Francisco de Paula Paranhos-Neto, Maria da Glória Costa Reis Monteiro de Barros, Miguel Madeira, Guilherme Alcantara Cunha Lima, Maria Lucia Fleiuss Farias
Rok vydání: 2016
Předmět:
Peak bone mass
medicine.medical_specialty
Endocrinology
Diabetes and Metabolism

Osteoporosis
lcsh:Medicine
chemistry.chemical_element
030209 endocrinology & metabolism
Calcium
Recommended Dietary Allowances
lcsh:Diseases of the endocrine glands. Clinical endocrinology
Bone and Bones
Fractures
Bone

03 medical and health sciences
cardiovascular safety
0302 clinical medicine
Calcium supplementation
Meta-Analysis as Topic
cardiovascular mortality
Bone Density
Risk Factors
Internal medicine
medicine
Humans
030212 general & internal medicine
Vitamin D
Dietary calcium
Randomized Controlled Trials as Topic
dietary calcium
lcsh:RC648-665
Bone Density Conservation Agents
medicine.diagnostic_test
business.industry
lcsh:R
Age Factors
medicine.disease
osteoporosis
Calcium
Dietary

Endocrinology
Blood pressure
chemistry
Cardiovascular Diseases
Dietary Supplements
Lipid profile
business
Hormone
Zdroj: Archives of Endocrinology and Metabolism, Vol 60, Iss 3, Pp 252-263
Archives of Endocrinology and Metabolism, Volume: 60, Issue: 3, Pages: 252-263, Published: JUN 2016
Archives of Endocrinology and Metabolism v.60 n.3 2016
Arquivos de Endocrinologia e Metabolismo
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
ISSN: 2359-3997
DOI: 10.1590/2359-3997000000173
Popis: The proper dietary calcium intake and calcium supplementation, when indicated, are important factors in the acquisition of peak bone mass during youth and in the prevention of fractures in old age. In addition to its deposition in bone, calcium confers an increase in its resistance and exhibits important activities in different enzymatic pathways in the body (e.g., neural, hormonal, muscle-related and blood clotting pathways). Thus, calcium supplementation can directly or indirectly affect important functions in the body, such as the control of blood pressure, plasma glucose, body weight, lipid profile and endothelial function. Since one publication reported increased cardiovascular risk due to calcium supplementation, many researchers have studied whether this risk actually exists; the results are conflicting, and the involved mechanisms are uncertain. However, studies that have evaluated the influence of the consumption of foods rich in calcium have reported no increase in the cardiovascular risk, which suggests that nutritional intake should be prioritized as a method for supplementation and that the use of calcium supplements should be reserved for patients who truly need supplementation and are unable to achieve the recommended daily nutritional intake of calcium.
Databáze: OpenAIRE