Calcium intake: good for the bones but bad for the heart? An analysis of clinical studies
Autor: | Priscilla Damião Araújo Lima, Lívia Paiva Vardiero, Elisa Fernandes de Melo, Francisco de Paula Paranhos-Neto, Maria da Glória Costa Reis Monteiro de Barros, Miguel Madeira, Guilherme Alcantara Cunha Lima, Maria Lucia Fleiuss Farias |
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Rok vydání: | 2016 |
Předmět: |
Peak bone mass
medicine.medical_specialty Endocrinology Diabetes and Metabolism Osteoporosis lcsh:Medicine chemistry.chemical_element 030209 endocrinology & metabolism Calcium Recommended Dietary Allowances lcsh:Diseases of the endocrine glands. Clinical endocrinology Bone and Bones Fractures Bone 03 medical and health sciences cardiovascular safety 0302 clinical medicine Calcium supplementation Meta-Analysis as Topic cardiovascular mortality Bone Density Risk Factors Internal medicine medicine Humans 030212 general & internal medicine Vitamin D Dietary calcium Randomized Controlled Trials as Topic dietary calcium lcsh:RC648-665 Bone Density Conservation Agents medicine.diagnostic_test business.industry lcsh:R Age Factors medicine.disease osteoporosis Calcium Dietary Endocrinology Blood pressure chemistry Cardiovascular Diseases Dietary Supplements Lipid profile business Hormone |
Zdroj: | Archives of Endocrinology and Metabolism, Vol 60, Iss 3, Pp 252-263 Archives of Endocrinology and Metabolism, Volume: 60, Issue: 3, Pages: 252-263, Published: JUN 2016 Archives of Endocrinology and Metabolism v.60 n.3 2016 Arquivos de Endocrinologia e Metabolismo Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) instacron:SBEM |
ISSN: | 2359-3997 |
DOI: | 10.1590/2359-3997000000173 |
Popis: | The proper dietary calcium intake and calcium supplementation, when indicated, are important factors in the acquisition of peak bone mass during youth and in the prevention of fractures in old age. In addition to its deposition in bone, calcium confers an increase in its resistance and exhibits important activities in different enzymatic pathways in the body (e.g., neural, hormonal, muscle-related and blood clotting pathways). Thus, calcium supplementation can directly or indirectly affect important functions in the body, such as the control of blood pressure, plasma glucose, body weight, lipid profile and endothelial function. Since one publication reported increased cardiovascular risk due to calcium supplementation, many researchers have studied whether this risk actually exists; the results are conflicting, and the involved mechanisms are uncertain. However, studies that have evaluated the influence of the consumption of foods rich in calcium have reported no increase in the cardiovascular risk, which suggests that nutritional intake should be prioritized as a method for supplementation and that the use of calcium supplements should be reserved for patients who truly need supplementation and are unable to achieve the recommended daily nutritional intake of calcium. |
Databáze: | OpenAIRE |
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