Popis: |
1.1. The effects of chronic pulmonary emphysema upon the lung volume measurements, mechanics of breathing, pulmonary gas exchange and nervous regulation of ventilation have been presented and discussed. 2.2. An attempt has been made to relate some of the physiologic disturbances to the pathologic findings and to the clinical picture in this disease. 3.3. The interrelationship between the various physiologic changes has been emphasized and four separate patterns of pulmonary insufficiency, previously reported, have been discussed briefly and illustrated by individual cases. 4.4. The important features of therapy have been outlined in each of the four patterns. Special emphasis has been placed upon the relief of arterial anoxia and carbon dioxide retention by correction of their main cause, i.e., inadequate alveolar ventilation rather than by oxygen therapy. The effect of oxygen inhalation upon the nervous regulation of ventilation has been discussed. |