Prevalence and Risk Factors for Polypoidal Choroidal Vasculopathy in a General Japanese Population: The Hisayama Study
Autor: | Yutaka Kiyohara, Koh Hei Sonoda, Jun Hata, Tatsuro Ishibashi, Kohta Fujiwara, Yuji Oshima, Sawako Hashimoto, Toshiharu Ninomiya, Miho Yasuda, Takeshi Yoshitomi |
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Rok vydání: | 2018 |
Předmět: |
Male
Time Factors Fundus Oculi 030204 cardiovascular system & hematology Risk Assessment complex mixtures 03 medical and health sciences 0302 clinical medicine Age Distribution Polyps Japan Risk Factors Prevalence Medicine Humans Fluorescein Angiography Sex Distribution business.industry Choroid General Medicine Choroid Diseases Japanese population eye diseases Population based study Ophthalmology Cross-Sectional Studies Population Surveillance 030221 ophthalmology & optometry Wet Macular Degeneration Female business Demography Follow-Up Studies |
DOI: | 10.6084/m9.figshare.6941366 |
Popis: | Purpose: To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. Methods: This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old were enrolled in this study. The characteristics of PCV were determined by fundus examination or based on indocyanine green and fluorescein angiographic findings. We evaluated the contributions of the risk factors for PCV. Results: Among the 207 participants with age-related macular degeneration (AMD), 174 (6.5%) had early AMD, and 33 (1.2%) had late AMD, including 10 participants with PCV (0.4%). Male and smoking habit were significant risk factors for the development of PCV. Conclusions: The prevalence of PCV is higher among Japanese subjects than Caucasians in Western countries. Male gender and smoking habit were significant risk factors for PCV in a general Japanese population. |
Databáze: | OpenAIRE |
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