Progressive supranuclear gaze palsy without parkinsonism: A case of neuro-Whipple
| Autor: | Anna Magherini, M. Leone, Roberta Pentore, Paolo Frigio Nichelli, Marco Grandi |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Sleep Wake Disorders medicine.medical_specialty Pediatrics Movement disorders Progressive supranuclear palsy Diagnosis Differential Biopsy medicine Humans Whipple disease gaze palsy Cognitive decline Aged medicine.diagnostic_test Parkinsonism Neuropsychology Parkinson Disease medicine.disease Magnetic Resonance Imaging Supranuclear gaze palsy nervous system diseases Surgery Neurology Supranuclear Palsy Progressive Neurology (clinical) Geriatrics and Gerontology medicine.symptom Cognition Disorders Psychology Myoclonus |
| Zdroj: | Parkinsonism & Related Disorders. 13:449-452 |
| ISSN: | 1353-8020 |
| DOI: | 10.1016/j.parkreldis.2006.05.035 |
| Popis: | We report the case of a 69-year-old man with a 7-month history of severe progressive supranuclear gaze palsy associated with mild cognitive decline and sleep disturbances, but not parkinsonism. After a period spent consulting a range of different specialists, the appearance of brachial myoclonus prompted his referral to a movement disorders specialist. Duodenum biopsy confirmed the suspicion of neuro-Whipple disease. Antibiotic therapy was started but the delay in the diagnosis proved fatal to this patient. This noteworthy case shows unusual neurological features of a rare but treatable disease, often misdiagnosed as progressive supranuclear palsy. |
| Databáze: | OpenAIRE |
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