Complications of chronic necrotizing pulmonary aspergillosis: review of published case reports
| Autor: | Aleksandra Barac, Tatjana Adzic Vukicevic, Vladimir Zugic, Aleksandra Ilic, Goran Stevanovic, Salvatore Rubino |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine Complications lcsh:RC955-962 030106 microbiology Disease Review medicine.disease_cause Aspergillosis Medical Records Mycobacterium tuberculosis Chronic necrotizing pulmonary aspergillosis 03 medical and health sciences Necrosis 0302 clinical medicine Silicosis medicine Humans 030212 general & internal medicine Invasive Pulmonary Aspergillosis biology business.industry Medical record Chronic pulmonary aspergillosis General Medicine biology.organism_classification medicine.disease Dermatology 3. Good health Surgery Infectious Diseases Aspergillus Pneumothorax Superinfection Chronic Disease business |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo Revista do Instituto de Medicina Tropical de São Paulo, Volume: 59, Article number: e19, Published: 13 APR 2017 Revista do Instituto de Medicina Tropical de São Paulo, Vol 59, Iss 0 Revista do Instituto de Medicina Tropical de São Paulo; Vol. 59 (2017); e19 Revista do Instituto de Medicina Tropical de São Paulo; v. 59 (2017); e19 Instituto de Medicina Tropical (IMT) instacron:IMT |
| ISSN: | 1678-9946 0036-4665 |
| Popis: | Chronic necrotizing pulmonary aspergillosis (CNPA), a form of chronic pulmonary aspergillosis (CPA), affects immunocompetent or mildly immunocompromised persons with underlying pulmonary disease. These conditions are associated with high morbidity and mortality and often require long-term antifungal treatment. The long-term prognosis for patients with CNPA and the potential complications of CNPA have not been well documented. The aim of this study was to review published papers that report cases of CNPA complications and to highlight risk factors for development of CNPA. The complications in conjunction associated with CNPA are as follows: pseudomembranous necrotizing tracheobronchial aspergillosis, ankylosing spondylarthritis, pulmonary silicosis, acute respiratory distress syndrome, pulmonary Mycobacterium avium complex (MAC) disease, superinfection with Mycobacterium tuberculosis, and and pneumothorax. The diagnosis of CNPA is still a challenge. Culture and histologic examinations of bronchoscopically identified tracheobronchial mucus plugs and necrotic material should be performed in all immunocompromised individuals, even when the radiographic findings are unchanged. Early detection of intraluminal growth of Aspergillus and prompt antifungal therapy may facilitate the management of these patients and prevent development of complications. |
| Databáze: | OpenAIRE |
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