A study of the potential interaction of valsartan with some electrolytes

Autor:	CJ Mbah
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	Partition coefficient chemistry.chemical_compound chemistry Valsartan Geography Planning and Development Inorganic chemistry Sodium fluoride medicine Electrolyte Potential interaction Valsartan Monovalent electrolytes Divalent electrolytes Management Monitoring Policy and Law medicine.drug Ion
Zdroj:	Bio-Research; Vol 7, No 1 (2009)
ISSN:	1596-7409
Popis:	The effect of electrolytes (salts) on the partition coefficient of valsartan was studied at room temperature. The investigation was done by partitioning valsartan between 1-octanol and electrolyte solutions of varying concentrations. It was found that all the electrolytes increased the partition coefficient of the drug except sodium fluoride. The effect was found to depend on the size and charge of the ions present in solution.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920bbf9130bc303e106ad479c25313e7 https://www.ajol.info/index.php/br/article/view/45465 Zobrazit plný text záznamu