Detection of major group rhinoviruses by soluble intercellular adhesion molecule-1 (sICAM-1)
Autor: | Vincent J. Merluzzi, Ronald B. Faanes, Kathleen Last-Barney, Deborah D. Jeanfavre, Eugene J. McNally, Steven D. Marlin, Carol Cahill |
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Rok vydání: | 1991 |
Předmět: |
Rhinovirus
Intercellular Adhesion Molecule-1 Biotin Enzyme-Linked Immunosorbent Assay Biology medicine.disease_cause Virus Microbiology Bacterial Proteins Cytopathogenic Effect Viral stomatognathic system Virology medicine Humans Receptor Cell adhesion molecule Adhesion stomatognathic diseases Biotinylation Receptors Virus Streptavidin Cell Adhesion Molecules Intracellular HeLa Cells |
Zdroj: | Journal of Virological Methods. 35:255-264 |
ISSN: | 0166-0934 |
Popis: | Soluble intercellular adhesion molecule-1 (sICAM-1) was shown to be the receptor for the major subgroup of rhinoviruses. It was demonstrated that this molecule can inhibit the binding and subsequent infection of target cells by rhinoviruses belonging to the major but not the minor subgroup. The data reported now describe an ELISA-based system utilizing biotinylated sICAM-1 as a means of detecting rhinoviruses belonging to the major subgroup. |
Databáze: | OpenAIRE |
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