Non-dietary environmental risk factors in prostate cancer
Autor: | E. Sobrino-Najul, O. Berbel-Tornero, J. Garcia-i-Castell, Juan Antonio Ortega-García, J. Ferrís-i-Tortajada, J.A. López-Andreu |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: |
Oncology
Adult Male medicine.medical_specialty Neoplasms Radiation-Induced Sexual Behavior Dietary factors Adenocarcinoma Article Cohort Studies Prostate cancer Electromagnetic Fields Environmental risk Meta-Analysis as Topic Risk Factors Primary prevention Internal medicine Occupational Exposure Epidemiology Vasectomy medicine Cadmium Compounds Anticarcinogenic Agents Humans Pesticides Aged Gynecology Cocarcinogenesis business.industry Smoking Case-control study Prostatic Neoplasms General Medicine Middle Aged medicine.disease Carcinogens Environmental Prostatitis Sexual behavior Socioeconomic Factors Case-Control Studies business Cohort study |
Popis: | The aim is to update and disclose the main environmental risk factors, excluding dietary factors, involved in the etiopathology of prostate cancer.Bibliographic review of the last 25 years of non-dietary environmental risk factors associated with prostate cancer between 1985 and 2010, obtained from MedLine, CancerLit, Science Citation Index and Embase. The search profiles were Environmental Risk Factors/Tobacco/Infectious-Inflammatory Factors/Pesticides/Vasectomy/Occupational Exposures/Chemoprevention Agents/Radiation and Prostate Cancer.While some non-dietary environmental risk factors increase the risk of acquiring the disease, others decrease it. Of the former, it is worth mentioning exposal to tobacco smoke, chronic infectious-inflammatory prostatic processes and occupational exposure to cadmium, herbicides and pesticides. The first factors that reduce the risk are the use of chemopreventive drugs (Finasterida, Dutasteride) and exposure to ultraviolet solar radiation. With the current data, a vasectomy does not influence the risk of developing the disease.The slow process of prostate carcinogenesis is the final result of the interaction of constitutional risk and environmental factors. Non-dietary environmental factors play an important role in the etiopathology of this disease. To appropriately assess the risk factors, extensive case studies that include all the possible variables must be analysed. |
Databáze: | OpenAIRE |
Externí odkaz: |