| Autor: |
Sihai Dave Zhao, Frida Corona, Hagai Y. Shpigler, Lindsey Block, Gene E. Robinson, Michael C. Saul, Amy Cash Ahmed |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Proceedings of the National Academy of Sciences of the United States of America. 116(35) |
| ISSN: |
1091-6490 |
| Popis: |
Sociobiological theory proposed that similarities between human and animal societies reflect similar evolutionary origins. We used comparative genomics to test this controversial idea by determining whether superficial behavioral similarities between humans and honey bees reflect shared molecular mechanisms. We found unique and significant enrichment for autism spectrum disorder-related genes in the neurogenomic signatures of a high-level integration center of the insect brain in bees unresponsive to two different salient social stimuli. These results demonstrate deep conservation for genes implicated in autism spectrum disorder in humans and genes associated with social responsiveness in honey bees. Comparative genomics thus provides a means to test theory on the biology of social behavior. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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