| Autor: |
Quan Zhao, Yaxin Long, Wen Cheng, Yingguang Huang, Jinyuan Li, Yuejin Li, Xing Li, Xiaodong Guo, Yu Li, Guosan Li, Kunmei Gong, Jian Zhang |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
International journal of oncology. 60(6) |
| ISSN: |
1791-2423 |
| Popis: |
5‑Fluorouracil (5‑FU) is the preferred chemotherapeutic drug used in the treatment of colon cancer; however, drug resistance affects its clinical efficacy. Visfatin, an adipokine that promotes tumour development, has the potential to increase resistance to chemotherapy. The present study aimed to verify the effects of visfatin on the sensitivity of colon cancer cells to 5‑FU and to elucidate the potential mechanisms involved. Tissue microarrays (TMAs) were used to analyse visfatin differential expression in normal colon and colon cancer tissues, and the data were further validated |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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