Systemic viral infection in children receiving chemotherapy for acute leukemia
| Autor: | Constanze Buus-Gehrig, Marc T. Hennies, Andreas H. Groll, Konrad Bochennek, Thomas Klingebiel, Thomas Lehrnbecher |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
viruses medicine.medical_treatment Congenital cytomegalovirus infection Hematopoietic stem cell transplantation medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Acute leukemia Chemotherapy biology Parvovirus business.industry Incidence (epidemiology) Varicella zoster virus virus diseases Hematology Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease biology.organism_classification Prognosis Leukemia Myeloid Acute Herpes simplex virus Oncology Virus Diseases 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Viruses business 030215 immunology |
| Zdroj: | Pediatric bloodcancerREFERENCES. 67(12) |
| ISSN: | 1545-5017 |
| Popis: | Systemic viral diseases frequently occur in allogeneic hematopoietic stem cell transplantation, but data in children receiving chemotherapy for acute leukemia are scarce. We therefore collected and analyzed the published data on symptomatic infection from cytomegalovirus, herpes simplex virus, varicella zoster virus, parvovirus B19, or adenovirus in pediatric acute leukemia. Reports on 68 children were identified, of whom 16 patients have died from the infection. Further studies have to (1) evaluate the true incidence of these infections in pediatric acute leukemia, (2) their impact on outcome, and (3) whether a subpopulation of patients could benefit from screening and prophylactic strategies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text