Efficacy of intravenous amiodarone in the management of paroxysmal or new atrial fibrillation with fast ventricular response
| Autor: | Alexander Arditti, Jacob Agmon, Samuel Sclarovsky, Ruben F. Lewin, Bela Buimovici, Boris Strasberg |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart Ventricles medicine.medical_treatment Amiodarone Electrocardiography Heart Rate Recurrence Internal medicine Atrial Fibrillation medicine Humans Infusions Parenteral Sinus rhythm cardiovascular diseases Aged Benzofurans Chemotherapy medicine.diagnostic_test business.industry Intravenous amiodarone Atrial fibrillation Middle Aged medicine.disease New onset atrial fibrillation Atrial Flutter Anesthesia Atrioventricular Node cardiovascular system Cardiology Female Cardiology and Cardiovascular Medicine business Atrial flutter medicine.drug |
| Zdroj: | International Journal of Cardiology. 7:47-55 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/0167-5273(85)90172-x |
| Popis: | We tested the efficacy of intravenous amiodarone (5 mg/kg) in slowing ventricular response and/or restoring sinus rhythm in 26 patients with paroxysmal or new atrial fibrillation with fast ventricular response. There were 16 men and 10 women with ages ranging from 35 to 84 years, mean 63 years. Intravenous amiodarone initially slowed the ventricular response in all patients from 143 +/- 27 to 96 +/- 10 beats/min (P less than 0.001). Twelve patients (46%) reverted to sinus rhythm within the first 30 min (range 5 to 30 min, mean 14 +/- 9 min). One patient reverted to atrial flutter after 10 min and 40 min later to sinus rhythm. Six patients (23%) converted to sinus rhythm after 2 to 8 hr and in these 6 cases, the initial slowing in ventricular response obtained with amiodarone persisted until conversion. Seven patients (27%) did not convert to sinus rhythm following amiodarone administration and they required further medical therapy to slow the ventricular response and/or to convert to sinus rhythm. No serious side effects from drug administration were noted. Intravenous amiodarone appears as a highly effective medication in the conversion or control of new onset atrial fibrillation with fast ventricular response. |
| Databáze: | OpenAIRE |
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