A comparative study of sphingolipids in transplanted melanomas with high and low metastatic activity
Autor: | E. V. Dyatlovitskaya, O. G. Somova, A. M. Kozlov, A. G. Kandyba |
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Rok vydání: | 2008 |
Předmět: |
Ceramide
Melanoma Experimental Biochemistry Mice Lactosylceramide chemistry.chemical_compound Molar ratio medicine Animals Bioorganic chemistry music neoplasms Sphingolipids music.instrument Melanoma Organic Chemistry medicine.disease Sphingolipid Mice Inbred C57BL Ganglioside GM3 chemistry Mice Inbred DBA lipids (amino acids peptides and proteins) Sphingomyelin Neoplasm Transplantation |
Zdroj: | Russian Journal of Bioorganic Chemistry. 34:230-233 |
ISSN: | 1573-9163 1068-1620 |
Popis: | The content of sphingolipids in M3 and B16/F10 melanomas with a high metastatic potential and in Claudman's and B16/F1 melanomas with a low metastatic potential was studied. It was shown that the content of total lipid-bound sialic acids and ganglioside GM3 in melanomas with a high metastatic potential is considerably higher than that in melanomas with a low metastatic potential. On the other hand, the ceramide to glucosylceramide molar ratio is higher in melanomas with a low metastatic potential. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2008, vol. 34, no. 2; see also http://www.maik.ru. |
Databáze: | OpenAIRE |
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