Independent Association of Erectile Dysfunction and Low Testosterone Levels with Life Dissatisfaction in Men with Chronic Spinal Cord Injury
| Autor: | Settimio D'Andrea, Giorgio Felzani, Sandro Francavilla, Felice Francavilla, Francesca Cavallo, Chiara Castellini, Arcangelo Barbonetti, E. Minaldi |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Tetraplegia medicine.medical_specialty Sexual Dysfunction Urology Endocrinology Diabetes and Metabolism Population 030232 urology & nephrology 03 medical and health sciences 0302 clinical medicine Endocrinology Erectile Dysfunction Quality of life Androgen deficiency Humans Medicine Testosterone Prospective Studies education Spinal cord injury Spinal Cord Injuries Paraplegia education.field_of_study 030219 obstetrics & reproductive medicine business.industry Penile Erection Androgen Deficiency Life satisfaction Testosterone (patch) medicine.disease Psychiatry and Mental health Sexual dysfunction Erectile dysfunction Reproductive Medicine Quality of Life Physical therapy medicine.symptom business |
| Zdroj: | The Journal of Sexual Medicine. 17:911-918 |
| ISSN: | 1743-6109 1743-6095 |
| DOI: | 10.1016/j.jsxm.2020.01.018 |
| Popis: | Background The loss of global functional independence, along with bladder, bowel, and sexual dysfunctions, may contribute to psychological distress and life dissatisfaction after spinal cord injury (SCI). Aim To explore the relationship of erectile function and androgenic status with life satisfaction, independently from confounders recognizable in spinal cord–injured men. Methods 100 consecutive men (49 ± 17 years) admitted to a rehabilitation program because of chronic SCI (≥1 year) underwent clinical/biochemical evaluations, including the assessment of life and sexual satisfaction using the Life-Satisfaction Questionnaire-9 (LiSat-9), erectile function using the International Index of Erectile Function-5 (IIEF-5), global and bowel-bladder functional independence using the Spinal Cord Independence Measure (SCIM) and measurement of total testosterone (TT) levels. The free testosterone level was calculated using the Vermeulen formula. Outcomes The outcomes include the relationship between sexual health and life satisfaction in men with SCI. Results A LiSat-9 score Clinical Implications In men with chronic SCI, assessment of erectile function and testosterone levels can help to predict life satisfaction. Strengths & Limitations This is the first demonstration of the independent association of androgen deficiency and ED with life satisfaction in men with SCI. Prospective studies are warranted to clarify the cause-effect relationships. Conclusions In men with SCI, ED and low testosterone levels exhibit a significant independent association with life dissatisfaction; longitudinal intervention studies could explore possible effects of their treatment in improving sexual and life satisfaction in this population. |
| Databáze: | OpenAIRE |
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