Relationship between erythrocyte sedimentation rate and choroidal and retinal thickness in Behçet's disease
| Autor: | Emine Pangal, Orhan Altunel, İsa Yuvacı, Fatmagül Ülkü Demir, Emel Güler, Ender Sirakaya, Nurettin Bayram, Mustafa Ataş |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Erythrocytes indices
Adult Male medicine.medical_specialty Sedimentação sanguínea Nerve fiber layer Nerve fiber Behçet syndrome Blood sedimentation Blood Sedimentation Behcet's disease Statistics Nonparametric Retina Uveitis Índices de eritrócitos Tomography optical coherence chemistry.chemical_compound Nerve Fibers Optical coherence tomography lcsh:Ophthalmology Reference Values Ophthalmology medicine Humans Prospective Studies Intraocular Pressure Coroide medicine.diagnostic_test Choroid business.industry Behcet Syndrome Retinal General Medicine medicine.disease eye diseases medicine.anatomical_structure chemistry Tomografia de coerência óptica lcsh:RE1-994 Case-Control Studies Erythrocyte sedimentation rate Female Síndrome de Behçet sense organs business Tomography Optical Coherence |
| Zdroj: | Arquivos Brasileiros de Oftalmologia, Iss 0 (2019) Arquivos Brasileiros de Oftalmologia v.82 n.4 2019 Arquivos brasileiros de oftalmologia Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO |
| ISSN: | 1678-2925 |
| Popis: | Purpose: To compare retinal and choroidal thickness in patients with Behçet's disease with and without ocular involvement as well as to evaluate the correlation between erythrocyte sedimentation rate and choroidal thickness among patients with Behçet's disease. Methods: This was a prospective interventional study investigating erythrocyte sedimentation as well as choroidal and retinal thickness among patients with Behçet's disease. Patients who were diagnosed based on The International Criteria for Behçet's Disease with (Group A) or without (Group B) ocular involvement and a matched control group (Group C) participated in the study. Optical coherence tomography measurements and blood tests were performed on the same day. Retinal and choroidal thickness were measured using spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering, Heidelberg, Germany), and central macular thickness, central subfoveal choroidal thickness, and retinal nerve fiber layer thickness were measured using optical coherence tomography. Results: Average erythrocyte sedimentation values were 9.89 mm/h in Group A, 16.21 mm/h in Group B, and 3.89 mm/h in Group C; average central subfoveal choroidal thickness values were 350.66, 331.74, and 325.95 mm, respectively. Average central macular thickness and retinal nerve fiber layer thickness values of patients in Groups A, B and C were 226.39 and 225.97mm; 234.11 and 92.00 mm; and 97.58 and 99.84 mm, respectively. No significant difference was seen between Group A and B patients in central subfoveal choroidal thickness, central macular thickness, or retinal nerve fiber layer thickness values. Central macular thickness was statistically significantly thinner in Groups A and B than in Group C (p=0.016). Group A had thinning in the nasal quadrant of the retinal and general retinal nerve fiber layers when compared with those in Group C (p=0.010 and 0.041, respectively). A connection could not be established between the erythrocyte sedimentation, central subfoveal choroidal thickness, central macular thickness, and retinal nerve fiber layer thickness in the patients with Behçet's disease. Conclusion: The erythrocyte sedimentation rate is typically used to test for activation of Behçet's disease and assess treatment response. In our study, we could not establish a connection between the erythrocyte sedimentation rate and central subfoveal choroidal thickness, central macular thickness, and retinal nerve fiber layer thickness in patients with systematically active Behçet's disease without ocular involvement. |
| Databáze: | OpenAIRE |
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