Assessing the Calf Pulmonary Function During a Long-Term Biventricular Assist Device Study with a Centrifugal Blood Pump
| Autor: | Yukihiko Nosé, Joerg Linneweber, Hiroshi Ishitoya, Julia Glueck, Daniel Oestmann, Seiji Ichikawa, Shinji Kawahito, Kenji Nonaka, Tadashi Motomura |
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| Rok vydání: | 2002 |
| Předmět: |
Lung Diseases
Pulmonary Circulation medicine.medical_specialty Time Factors Respiratory rate Biomedical Engineering Medicine (miscellaneous) Centrifugation Bioengineering Pulmonary Artery Pulmonary function testing Biomaterials Internal medicine medicine.artery Animals Medicine Pulmonary Wedge Pressure Pulmonary wedge pressure Oxygen saturation (medicine) medicine.diagnostic_test business.industry General Medicine Auscultation Disease Models Animal Blood pressure Pulmonary artery Cardiology Arterial blood Cattle Heart-Assist Devices Blood Gas Analysis business Blood Flow Velocity |
| Zdroj: | Artificial Organs. 26:924-926 |
| ISSN: | 1525-1594 0160-564X |
| DOI: | 10.1046/j.1525-1594.2002.07123.x |
| Popis: | Pulmonary congestion due to inappropriate pump flow management is one major problem necessary to avoid during long-term biventricular assist device (BVAD) implantation. Our objective was to assess the effects of pulmonary arterial flow rate and flow rates of both (right and left) bypass pumps. Six healthy calves, which had been implanted with a BVAD system, were selected for this retrospective study. Pulmonary artery flows, both pump flow rates, oxygen saturation of the arterial blood, and pulmonary arterial pressures were assessed as parameters of pulmonary function as was routine clinical evaluation of respiratory rate and character and chest auscultation. The average pulmonary artery flow rate (PAF), systolic pressure of pulmonary artery (sPAP), and oxygen saturation were 148.8 ml/kg per min, 35.1 mm Hg, and 95.3%, respectively. Pulmonary dysfunction occurred in one case, in which the mean PAF, sPAP, and oxygen saturation were 169 ml/kg per min, 66.1 mm Hg, and 90.9%, respectively. The ratio for the right/left pump flow rate (R/L ratio) for the case having pulmonary dysfunction was 1.57 even though the ratio for the other cases was less than 1. Maintaining an R/L ratio less than 1 and/or PAF less than 160 ml/kg per min and PAP less than 50 mm Hg is recommended as the initial conditions to target to avoid pulmonary dysfunction during a BVAD implantation with a beating heart condition. |
| Databáze: | OpenAIRE |
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