Comparison of two automated oxygen controllers in oxygen targeting in preterm infants during admission: an observational study

Autor: Hylke H Salverda, Janneke Dekker, Enrico Lopriore, Peter A Dargaville, Steffen C Pauws, Arjan B te Pas
Přispěvatelé: Language, Communication and Cognition
Rok vydání: 2023
Předmět:
Zdroj: Archives of Disease in Childhood. Fetal and Neonatal Edition. BMJ Publishing Group
ISSN: 1468-2052
1359-2998
DOI: 10.1136/archdischild-2022-324819
Popis: ObjectiveTo compare the effect of two different automated oxygen control devices on time preterm infants spent in different oxygen saturation (SpO2) ranges during their entire stay in the neonatal intensive care unit (NICU).DesignRetrospective cohort study of prospectively collected data.SettingTertiary level neonatal unit in the Netherlands.PatientsPreterm infants (OxyGenie 75 infants, CLiO2111 infants) born at 24–29 weeks’ gestation receiving at least 72 hours of respiratory support between October 2015 and November 2020.InterventionsInspired oxygen concentration was titrated by the OxyGenie controller (SLE6000 ventilator) between February 2019 and November 2020 and the CLiO2controller (AVEA ventilator) between October 2015 and December 2018 as standard of care.Main outcome measuresTime spent within SpO2target range (TR, 91–95% for either epoch) and other SpO2ranges.ResultsTime spent within the SpO2TR when receiving supplemental oxygen was higher during OxyGenie control (median 71.5 [IQR 64.6–77.0]% vs 51.3 [47.3–58.5]%, p298%: 1.0 [0.5–2.4]% vs 4.0 [2.0–7.9]%, p2(29.5 [28.0–33.2]% vs 29.6 [27.7–32.1]%, p=not significant).ConclusionsOxygen saturation targeting was significantly different in the OxyGenie epoch in preterm infants, with less time in hypoxic and hyperoxic SpO2ranges during their stay in the NICU.
Databáze: OpenAIRE