UK Medical Cannabis Registry: an analysis of clinical outcomes of medicinal cannabis therapy for generalized anxiety disorder

Autor:	Mehmet Ergisi, Simon Erridge, Michael Harris, Michal Kawka, Devaki Nimalan, Oliver Salazar, Katerina Loupasaki, Rayyan Ali, Carl Holvey, Ross Coomber, Michael Platt, James J Rucker, Mikael H Sodergren
Rok vydání:	2022
Předmět:	Quality of Life Humans Pharmacology (medical) Medical Marijuana Registries General Medicine General Pharmacology Toxicology and Pharmaceutics Anxiety Disorders Cannabis Endocannabinoids
Zdroj:	Expert Review of Clinical Pharmacology. 15:487-495
ISSN:	1751-2441 1751-2433
DOI:	10.1080/17512433.2022.2020640
Popis:	Objectives Anxiety disorders are one of the most common reasons for seeking treatment with cannabis-based medicinal products (CBMPs). Current pharmacological treatments are variable in efficacy and the endocannabinoid system has been identified as a potential therapeutic target. This study aims to detail the changes in health-related quality-of-life (HRQoL) and clinical safety following CBMP therapy for generalized anxiety disorder. Methods A case series from the UK Medical Cannabis Registry was performed. Primary outcomes included changes from baseline in patient-reported outcome measures (the General Anxiety Disorder Scale (GAD-7), EQ-5D-5L (a measure of health-related quality of life), and Sleep Quality Scale (SQS)) at 1, 3 and 6 months. Statistical significance was defined as p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9056549d772d590d13bc3c1a513e0278 https://doi.org/10.1080/17512433.2022.2020640 Zobrazit plný text záznamu