High-dynamic-range blood flow rate measurement in a large-diameter vessel
| Autor: | Xiao Cao Gao, Yong Bi, Wei Nan Gao, Yuan Yuan, Min Yuan Sun |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
Dynamic range business.industry Phantoms Imaging Optical Imaging Blood flow Ghost imaging Atomic and Molecular Physics and Optics Light scattering Speckle pattern Optics Dynamic light scattering Regional Blood Flow Laser-Doppler Flowmetry Animals Blood Vessels Humans Electrical and Electronic Engineering business Rheology Engineering (miscellaneous) Decorrelation High dynamic range Blood Flow Velocity |
| Zdroj: | Applied optics. 60(23) |
| ISSN: | 1539-4522 |
| Popis: | We propose a new, to the best of our knowledge, compound technique to measure high-dynamic-range blood flow rate in a large-diameter vessel, which combines the dynamic scattering light (DLS) and the laser speckle contrast imaging (LSCI) methods, possessing the advantages of the high temporal resolution of DLS and the robust property of LSCI. By controlling the second-order spatial correlations of the laser speckle through two imaging systems, the speckle temporal intensity autocorrelation function g 2 ( t ) and the decorrelation time τ c are directly measured using a high-speed camera. It turns out the enhanced spatial second-order correlation helps to measure the blood flow with higher dynamic range and that the measured parameter β and the blood flow dynamics n were accurately determined. For further improvement the dynamic range, the modified LSCI method was adopted, and the decorrelation time as a function of blood flow rate was constructed. It reveals the feasibility of measuring the high flow rate in large-diameter vessels and provides significant guidance for the future biomedical study of the myocardial perfusion in coronary artery bypass grafting, ghost imaging, and ghost cytometry. |
| Databáze: | OpenAIRE |
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