Transient expression of β-NADPH diaphorase in developing rat dorsal root ganglia neurons
| Autor: | James E. Vaughn, Richard Wetts |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Time Factors
Central nervous system Biology Nitric oxide Rats Sprague-Dawley Embryonic and Fetal Development chemistry.chemical_compound Developmental Neuroscience Dorsal root ganglion Ganglia Spinal Diaphorase medicine Animals Neurons NADPH dehydrogenase Embryogenesis NADPH Dehydrogenase Spinal cord Molecular biology Rats Nitric oxide synthase medicine.anatomical_structure chemistry biology.protein Amino Acid Oxidoreductases Nitric Oxide Synthase Neuroscience Developmental Biology |
| Zdroj: | Developmental Brain Research. 76:278-282 |
| ISSN: | 0165-3806 |
| DOI: | 10.1016/0165-3806(93)90219-z |
| Popis: | We report here that during early fetal rat development, most, if not all, dorsal root ganglion (DRG) cells were stained by the β-NADPH diaphorase histochemical reaction, indicating that they expressed nitric oxide synthase. During late fetal development, most DRG cells lost their diaphorase activity, but a small subset (located in all DRGs, but primarily in mid-thoracic DRGs) remained diaphorase-positive in adult animals. The transient expression of this enzyme suggests that nitric oxide may play a role during development that differs from its function in mature cells. |
| Databáze: | OpenAIRE |
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