Studies on the Synthetic Utility of [6 + 3] Cycloaddition of Pentafulvenes with 3-Oxidopyrylium Betaines: Efficient Synthesis of Fused Ring Cyclooctanoids

Autor:	Kokkuvayil Vasu Radhakrishnan, Mohanlal Smitha, K. Syam Krishnan, Eringathodi Suresh
Rok vydání:	2007
Předmět:	Chemistry Organic Chemistry chemistry.chemical_element General Medicine Ring (chemistry) Biochemistry Combinatorial chemistry Cycloaddition Luche reduction Drug Discovery Organic chemistry Molecule Carbon Diels–Alder reaction
Zdroj:	ChemInform. 38
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.200715127
Popis:	A study on the synthetic utility of [6+3] cycloaddition of pentafulvenes with 3-oxidopyrylium betaines is described. 5–8 Fused oxa-bridged cyclooctanoids, the products of the above methodology undergo facile Diels–Alder reaction, dipolar cycloaddition, Luche reduction and selective hydrogenation over Pd/C leading to functionalized molecules, which can be transformed to oxa-bridged fused cyclooctanoids. We have shown that the carbon framework of the molecules can be directly expanded from the product, thus enhancing the synthetic versatility of the products.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7edf0103c4db802bda19bc13d853b8 https://doi.org/10.1002/chin.200715127 Zobrazit plný text záznamu Plný text