Mean Platelet Volume Is Increased in Patients With Deep Vein Thrombosis

Autor: Mehmet Gulcan, Fatih Aksoy, Mustafa Etli, Mustafa Kayan, Ercan Varol
Rok vydání: 2011
Předmět:
Zdroj: Clinical and Applied Thrombosis/Hemostasis. 18:427-430
ISSN: 1938-2723
1076-0296
DOI: 10.1177/1076029611427437
Popis: Pulmonary thromboembolism is a serious complication in patients with deep vein thrombosis (DVT). Previous studies have demonstrated that platelet activation occurs in patients with DVT. Mean platelet volume (MPV) is a simple and easy method of assessing platelet function. The aim of this study was to assess the MPV, an indicator of platelet activation in patients with DVT.The study group consisted of 52 patients with newly diagnosed acute DVT. An age-, gender-, and body mass index-matched control group consisted of 30 healthy volunteers. All patients and control participants underwent ultrasonographic examination. We measured the serum MPV values in patients with DVT and control participants.Mean platelet volume was significantly higher among patients with DVT when compared with the control group (8.6 ± 0.8 vs 7.7 ± 0.9 fL, respectively; P.001).We have shown that MPV was significantly elevated in patients with DVT compared to controls.
Databáze: OpenAIRE