Spatial dynamics of bovine tuberculosis in the Autonomous Community of Madrid, Spain (2010-2012)
| Autor: | Rosa Diaz, Jesus Carpintero, Lucas Domínguez, Maria Luisa de la Cruz, Andres M. Perez, Carmen Casal, Javier Bezos, Beatriz Romero, Enrique Pages, Christopher M. Barker, Julio Alvarez |
|---|---|
| Přispěvatelé: | Sola, Christophe |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Veterinary medicine
Veterinary Microbiology lcsh:Medicine Disease Outbreaks law.invention law Zoonoses 2.2 Factors relating to the physical environment Bovine Tuberculosis Animal Husbandry Aetiology lcsh:Science Genetic Fingerprinting Mycobacterium bovis Multidisciplinary biology Epidemiological Factors Gram Positive Bacteria Bovine Subtyping 3. Good health Infectious Diseases Transmission (mechanics) Veterinary Diseases Infection Research Article General Science & Technology Animal Types Genetic Fingerprinting and Footprinting Large Animals Spatial distribution Microbiology Veterinary Epidemiology Rare Diseases Animals Tuberculosis Molecular Biology Techniques Molecular Biology Spatial analysis Prevention lcsh:R Biology and Life Sciences Outbreak Bacteriology biology.organism_classification Molecular Typing Spain Herd Veterinary Science Cattle lcsh:Q Veterinaria Tuberculosis Bovine |
| Zdroj: | PLoS ONE, Vol 9, Iss 12, p e115632 (2014) E-Prints Complutense: Archivo Institucional de la UCM Universidad Complutense de Madrid E-Prints Complutense. Archivo Institucional de la UCM instname PloS one, vol 9, iss 12 PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Progress in control of bovine tuberculosis (bTB) is often not uniform, usually due to the effect of one or more sometimes unknown epidemiological factors impairing the success of eradication programs. Use of spatial analysis can help to identify clusters of persistence of disease, leading to the identification of these factors thus allowing the implementation of targeted control measures, and may provide some insights of disease transmission, particularly when combined with molecular typing techniques. Here, the spatial dynamics of bTB in a high prevalence region of Spain were assessed during a three year period (2010-2012) using data from the eradication campaigns to detect clusters of positive bTB herds and of those infected with certain Mycobacterium bovis strains (characterized using spoligotyping and VNTR typing). In addition, the within-herd transmission coefficient (β) was estimated in infected herds and its spatial distribution and association with other potential outbreak and herd variables was evaluated. Significant clustering of positive herds was identified in the three years of the study in the same location ("high risk area"). Three spoligotypes (SB0339, SB0121 and SB1142) accounted for >70% of the outbreaks detected in the three years. VNTR subtyping revealed the presence of few but highly prevalent strains within the high risk area, suggesting maintained transmission in the area. The spatial autocorrelation found in the distribution of the estimated within-herd transmission coefficients in herds located within distances |
| Databáze: | OpenAIRE |
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