Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis
| Autor: | Amanda F. Marsch, Jennifer Yuan Sui, Brittany E. Yee, Phillip Q. Richards |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
chemistry.chemical_element Dermatology Zinc 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Acne Vulgaris medicine Humans Organic Chemicals Acne business.industry Diagnostic Tests Routine Incidence (epidemiology) Papule General Medicine medicine.disease Hidradenitis chemistry Rosacea 030220 oncology & carcinogenesis Meta-analysis Adjunctive treatment medicine.symptom business |
| Zdroj: | Dermatologic therapyREFERENCES. 33(6) |
| ISSN: | 1529-8019 |
| Popis: | Oral and topical zinc have been used for the treatment of acne, but there is a lack of definitive evidence for their efficacy. (a) To determine if mean serum zinc levels differ between acne patients and controls and (b) to determine the efficacy of zinc preparations in the treatment of acne. A systematic review and meta-analysis was performed according to recommended PRISMA [Preferred Reporting Items for Systematic Reviews and Meta-Analyses] guidelines. Subjects with acne had significantly lower serum zinc levels compared to controls. Patients who were treated with zinc had a significant improvement in mean inflammatory papule count compared to those who were not treated with zinc. There was no significant difference in the incidence of side effects in zinc supplementation vs comparators. Acne patients have decreased serum zinc levels. Zinc is effective for the treatment of acne, particularly at decreasing the number of inflammatory papules, when used as monotherapy or as an adjunctive treatment. |
| Databáze: | OpenAIRE |
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