Characterization of Left Ventricle Function by Analysis of Pressure Responses to Steps in Rotational Speed of the Hemopump®
| Autor: | Herman B. K. Boom, E.E. Kunst, Jan A. van Alste, T. Arts |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
Materials science medicine.medical_treatment Biomedical Engineering Time constant Medicine (miscellaneous) Bioengineering Rotational speed General Medicine Elastance Biomaterials medicine.anatomical_structure Ventricle Internal medicine Ventricular assist device cardiovascular system medicine Cardiology Ventricular pressure Ventricular volume Hemopump |
| Zdroj: | International journal of artificial organs, 17(4), 215-223. Wichtig Publishing |
| ISSN: | 1724-6040 0391-3988 |
| DOI: | 10.1177/039139889401700405 |
| Popis: | Optimizing the procedure of weaning the left ventricle from a left ventricular assist device requires the determination of the momentaneous condition of the left ventricle. In sheep, a method was developed to momentaneously quantify the left ventricular condition. The left ventricular pump condition was quantified by the time-varying parameters elastance and resistance. They were determined from perturbations in the left ventricular pressure of two subsequent beats induced by changes in flow of the assist device. The end-diastolic volume of the ventricle was estimated without directly measuring ventricular volume. Maximum elastance and resistance were 201.3 ± 32.7 [Palmi] and 12.3 ± 1.6 [Pa·s/ml], respectively (mean ± SE). The ventricular time constant, defined by the ratio of resistance to elastance, was 84.6 ± 17.1 [ms] (man ± SE). |
| Databáze: | OpenAIRE |
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