The role of symptomatic colds in asthma exacerbations: Influence of outdoor allergens and air pollutants
| Autor: | Marilyn Okada, Susan M. Tarlo, Paul Corey, Christine A. Rogers, A. Irvin Broder, Alexander C. Ferguson, Allan B. Becker, Jure Manfreda, Moira Chan-Yeung |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Male medicine.medical_specialty Allergy Adolescent Immunology Common Cold medicine.disease_cause Nitric Oxide Allergen Air pollutants immune system diseases Internal medicine Epidemiology Immunology and Allergy Medicine Humans Sulfur Dioxide Child Asthma Air Pollutants Asthma exacerbations business.industry Respiratory disease Rhinitis Allergic Seasonal Common cold Allergens Middle Aged medicine.disease respiratory tract diseases Female business |
| Zdroj: | The Journal of allergy and clinical immunology. 108(1) |
| ISSN: | 0091-6749 |
| Popis: | Both air pollutants and respiratory viral infections have been recognized to be important triggers of asthma exacerbations, but the possible interaction of these has not been assessed in an epidemiologic study.In this study, we aimed to assess the possible associations of symptomatic colds with outdoor allergens and air pollutants in exacerbating asthma.A total of 57 adults and children with asthma participated in a 1-year study in Vancouver, British Columbia. Diary cards recording symptoms of asthma and colds, medication usage, and peak expiratory flow rates were completed twice daily. Outdoor air pollutant levels and levels of pollen and fungal spores were measured. Levels were examined for associations with exacerbations of asthma with symptoms of a cold, as compared with asthma exacerbations with no cold symptoms and colds in the absence of asthma exacerbations.Of 130 asthma exacerbations, 47% were associated with cold symptoms (accounting for 44% of episodes of colds). Asthma exacerbations with colds were associated with higher levels of sulfur dioxide, and nitric oxide during March to November in comparison with asthma exacerbations without cold symptoms (P.018). Cold-symptom days overall were more common in winter and were significantly associated with lower temperatures, lower ozone levels, and higher sulfur dioxide, nitrogen dioxide, nitrogen oxide (NO and NO(x)), and carbon monoxide levels.Asthma exacerbations are commonly associated with cold symptoms. These episodes are associated with higher levels of sulfur dioxide and nitrogen oxides from March to November in comparison with asthma exacerbations without cold symptoms. |
| Databáze: | OpenAIRE |
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