The Use of Tertiary Alkylmagnesium Nucleophiles in Ni-Catalyzed Cross-Coupling Reactions

Autor:	Mark R. Biscoe, Amruta Joshi-Pangu
Rok vydání:	2012
Předmět:	chemistry.chemical_classification Aryl Organic Chemistry Grignard reaction Homogeneous catalysis Medicinal chemistry Article Coupling reaction Catalysis chemistry.chemical_compound Nucleophile chemistry Organic chemistry Carbene Alkyl
Zdroj:	Synlett. 23:1103-1107
ISSN:	1437-2096 0936-5214
Popis:	Nickel-catalyzed cross-coupling reactions of unactivated tertiary alkyl nucleophiles and aryl bromides have been developed using N-heterocyclic carbene ligands. These processes are reviewed alongside earlier attempts to employ unactivated tertiary alkyl nucleophiles in cross-coupling reactions. Potential mechanisms for the transformations, and future challenges in this field are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9db6e7488a88ad5f00df9a4067234c https://doi.org/10.1055/s-0031-1290765 Zobrazit plný text záznamu