Resection of secondary pulmonary malignancies in head and neck cancer patients
| Autor: | H. van Tinteren, T.W. Geurts, Houke M. Klomp, B Y Roukema, A.J.M. Balm, Sjaak Burgers |
|---|---|
| Přispěvatelé: | Ear, Nose and Throat |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Lung Neoplasms Adenocarcinoma of Lung Kaplan-Meier Estimate Adenocarcinoma Malignancy medicine Carcinoma Humans Survival rate Aged business.industry Head and neck cancer Cancer Neoplasms Second Primary General Medicine Middle Aged medicine.disease Prognosis Head and neck squamous-cell carcinoma Confidence interval Surgery Survival Rate Treatment Outcome Otorhinolaryngology Head and Neck Neoplasms Carcinoma Squamous Cell Female business |
| Zdroj: | Journal of laryngology and otology, 124(12), 1278-1283. Cambridge University Press |
| ISSN: | 0022-2151 |
| DOI: | 10.1017/s0022215110001064 |
| Popis: | Background:This study aimed to evaluate a single institute's experience with resection of metachronous pulmonary malignancy in patients treated for squamous cell carcinoma of the head and neck.Methods:Sixty-three consecutive patients treated curatively for head and neck squamous cell carcinoma underwent surgical resection of malignant lung lesions. Survival was estimated and potential prognostic factors investigated.Results:The median overall survival for the total group was 22.2 months. Fifty-one patients (81 per cent) had one lung lesion, while the remainder had multiple lesions (range, two to seven). In the 63 patients, 35 lobectomies, 4 pneumonectomies and 24 wedge resections were performed. For patients with pulmonary squamous cell carcinoma (n = 52), the three-year survival rate was 35 per cent (95 per cent confidence interval, 22–48); for patients with resected adenocarcinoma (n = 10), it was 50 per cent (95 per cent confidence interval, 18–75). The overall five-year survival rate was 30 per cent (95 per cent confidence interval, 19–42).Conclusion:In patients treated curatively for head and neck squamous cell carcinoma, resection of secondary pulmonary cancer is associated with favourable long term overall survival, especially for patients with adenocarcinoma lesions. |
| Databáze: | OpenAIRE |
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