Long term follow-up of 799 children with isolated ventricular septal defects
| Autor: | Hakan Poyrazoğlu, Nazan Özbarlas, Sevcan Erdem, Orhan Kemal Salih, Osman Küçükosmanoğlu |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Heart Septal Defects
Ventricular Male medicine.medical_specialty Adolescent Turkey Long term follow up Severity of Illness Index Aortic Valve Prolapse Postoperative Complications Internal medicine Severity of illness Humans Medicine Longitudinal Studies Atrium (heart) Child Heart septal defect Natural course business.industry Infant Newborn Infant Mean age medicine.disease medicine.anatomical_structure Child Preschool Cardiology Female Cardiology and Cardiovascular Medicine business Pediatric cardiology Follow-Up Studies |
| Zdroj: | Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology. 40:22-25 |
| ISSN: | 1308-4488 1016-5169 |
| DOI: | 10.5543/tkda.2012.01679 |
| Popis: | Objectives We evaluated long-term follow-up results and prognosis of pediatric patients with isolated ventricular septal defects (VSD). Study design The study included 799 patients (368 girls, 431 boys; mean age at diagnosis 24.3±37.4 months; median 6 months) who were monitored by the pediatric cardiology department for VSD. The mean follow-up period was 32.8±30.3 months (median 20 months). Results The VSDs were classified as perimembranous (n=610, 76.4%), muscular (n=171, 21.4%), doubly committed subarterial (n=10, 1.3%), and multiple (n=8, 1%). Spontaneous closure rates were 42.7%, 13.1%, and 25% in muscular, perimembranous, and multiple VSDs, respectively, which corresponded to a mean age of 18.6±19.9 months (median 12 months) in muscular and 30.2±33.7 months (median 14.5 months) in perimembranous VSDs. Before 2 years of age, 78.1% of muscular and 58.6% of perimembranous VSDs underwent spontaneous closure. Of 256 defects (32%) that required surgical closure, 91.4% were of perimembranous location. The mean age at surgery was 38.8±49.1 months (median 11 months) for muscular, and 43.7±40.9 months (median 24 months) for perimembranous defects. During the follow-up period, the following complications were noted: aortic valve prolapse (0.7%), aortic regurgitation (0.6%), left ventricle-to-right atrium shunt (2.6%), subaortic ridge (3.7%), and infundibular stenosis (1.2%). Aortic regurgitation developed in eight patients (3.7%) after surgical closure. Conclusion Our data on the natural course and prognosis of VSDs may be of relevance with respect to patients' age, defect type, and complications encountered in the follow-up period. |
| Databáze: | OpenAIRE |
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