Mistabron effects on platelets and blood coagulation
Autor: | Gregory W. Taylor, Raymond L. Henry, Mark A Washnock |
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Rok vydání: | 1984 |
Předmět: |
Platelet Aggregation
Stimulation Pharmacology Biochemistry chemistry.chemical_compound In vivo Medicine Animals Humans Platelet Blood Coagulation Mesna Mercaptoethanol business.industry Biochemistry (medical) Biological activity Cell Biology General Medicine Rats Epinephrine Coagulation chemistry Immunology Arachidonic acid Blood Coagulation Tests business medicine.drug |
Zdroj: | The Journal of international medical research. 12(5) |
ISSN: | 0300-0605 |
Popis: | The mucolytic drug Mistabron is often used in bleeding situations. The purpose of this study is to assess the safety of this drug in such circumstances. The platelet function of human blood is not impaired by clinically used Mistabron dosage, after stimulation with epinephrine, ADP or arachidonic acid. Coagulation proteins are not modified by Mesna, neither in vitro (bloodfrom human beings), nor in vivo (rats). |
Databáze: | OpenAIRE |
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