Effects of a citrus based juice on biomarkers of oxidative stress in metabolic syndrome patients
| Autor: | Cristina García-Viguera, Pilar Zafrilla, José Abellán, Juana Mulero, Francisco Avilés, Juana Bernabé, Begoña Cerdá, Angel Gil-Izquierdo, Soledad Parra, Diego A. Moreno |
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| Rok vydání: | 2013 |
| Předmět: |
Protein carbonyl content
GSH/GSSH Protein Carbonyl Content Medicine (miscellaneous) medicine.disease_cause Placebo chemistry.chemical_compound medicine TX341-641 In patient Food science 15-Isoprostane F2 Nutrition and Dietetics Nutrition. Foods and food supply Chemistry food and beverages Glutathione medicine.disease Metabolic syndrome Biochemistry Oxidative stress Aronia Oxidized ldl 8-OHdG Food Science |
| Zdroj: | Journal of Functional Foods, Vol 5, Iss 3, Pp 1031-1038 (2013) |
| ISSN: | 1756-4646 |
| DOI: | 10.1016/j.jff.2013.02.003 |
| Popis: | Bioactive substances found in numerous foods can be successfully and safely used to modify various cellular functions and affect the oxidative stress. The aim of this study was to analyze the effect of a citrus-based juice (juice citrus (95%) with 5% of aronia extract (Aronia melanocarpa)) on biomarkers of oxidative stress in patients with metabolic syndrome compared with healthy individuals. The study comprised 20 healthy subjects and 33 patients with metabolic syndrome. Eighteen patients consumed daily 300 mL of a citrus-based juice during 6 months and 15 patients consumed 300 mL of a placebo beverage. The control group consumed a citrus-based juice (CJ). Before, and at sixth months after consuming of a citrus-based juice the following parameters were determined: 15-isoprostane F2, 8-hydroxydeoxyguanosine (8-OHdG), reduced and oxidized glutathione (GSH/GSSH), carbonyl groups and oxidized LDL (ox-LDL). After consuming CJ during 6 months the values of 8-OHdG, carbonyl groups and LDL-ox decreased in both analyzed groups and the values of GSH/GSSH increased. Significant differences were observed in both groups. Thus consumption of citrus-based juice improved the biomarkers of oxidative stress in metabolic syndrome patients. |
| Databáze: | OpenAIRE |
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