Effect of flaxseed supplementation on blood pressure: a systematic review, and dose–response meta-analysis of randomized clinical trials
| Autor: | Lingou Li, Hanzhang Li, Yuzhen Gao, Somayeh vafaei, Xingyu Zhang, Mei Yang |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Food & Function. 14:675-690 |
| ISSN: | 2042-650X 2042-6496 |
| DOI: | 10.1039/d2fo02566c |
| Popis: | Many clinical trials have revealed that flaxseed supplementation might exert a potent antihypertensive influence, but the findings are inconsistent. In this regard, a meta-analysis was carried out to provide a more accurate estimate of the impact of flaxseed supplementation on blood pressure. We searched international databases including PubMed, Cochrane Library, Web of Science, Scopus, Embase, and Google Scholar till July 2022. A random-effects model was used to calculate weighted mean differences (WMDs). Non-linear dose-response analysis and meta-regression were performed. Meta-analysis of 33 trials (comprising 43 treatment arms) with 2427 participants revealed significant reductions in both systolic (WMD: -3.19 mmHg; 95% CI: -4.15 to -2.24 |
| Databáze: | OpenAIRE |
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