Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review
| Autor: | Kevin D. Croft, Joshua R. Lewis, Jonathan M. Hodgson, Marc Sim, Claire R. Palmer, Natalie C. Ward, Lauren C. Blekkenhorst, Carl Schultz |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Vitamin medicine.medical_specialty Vitamin K Physiology Inflammation Disease 030204 cardiovascular system & hematology Recommended Dietary Allowances Reference Daily Intake Bone remodeling 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Functional Food Epidemiology medicine Humans Cause of death 030109 nutrition & dietetics business.industry General Medicine Clinical trial chemistry Cardiovascular Diseases Dietary Supplements medicine.symptom business Food Science |
| Zdroj: | Foodfunction. 11(4) |
| ISSN: | 2042-650X |
| Popis: | Cardiovascular disease is the leading cause of death and disability worldwide. Recent work suggests a link between vitamin K insufficiency and deficiency with vascular calcification, a marker of advanced atherosclerosis. Vitamin K refers to a group of fat-soluble vitamins important for blood coagulation, reducing inflammation, regulating blood calcium metabolism, as well as bone metabolism, all of which may play a role in promoting cardiovascular health. Presently, there is a lack of a comprehensive vitamin K database on individual foods, which are required to accurately calculate vitamin K1 and K2 intake for examination in epidemiological studies. This has likely contributed to ambiguity regarding the recommended daily intake of vitamin K, including whether vitamin K1 and K2 may have separate, partly overlapping functions. This review will discuss the presence of: (i) vitamin K1 and K2 in the diet; (ii) the methods of quantitating vitamin K compounds in foods; and (iii) provide an overview of the evidence for the cardiovascular health benefits of vitamin K in observational and clinical trials. |
| Databáze: | OpenAIRE |
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