Trends in mortality rates of colorectal cancer in central Serbia during the period 1999-2014: A joinpoint regression analysis
| Autor: | Zoran Krivokapic, Marijana Banašević, Alja Pislar, Aleksandar Pavlović, Jadranka Maksimovic, Aleksandra Nikolic, Sandra Šipetić-Grujičić |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Joinpoint regression Colorectal cancer business.industry Mortality rate Public health Cancer colorectal cancer medicine.disease mortality 3. Good health 03 medical and health sciences 0302 clinical medicine Standardized mortality ratio trend Colon carcinoma colon cancer joinpoint regression Mortality data 030220 oncology & carcinogenesis medicine 030211 gastroenterology & hepatology business rectal cancer Demography |
| Zdroj: | Zdravstvena zaštita (2019) 48(3):33-42 |
| ISSN: | 0350-3208 |
| Popis: | Introduction/Aim: Colorectal cancer is the third most common cancer in men and the second most common cancer in women worldwide and one of the major causes of cancer-related mortality. The aim of this study was to analyze the trends in mortality rates of colorectal cancer in central Serbia in the period 1999-2014. Methods: Mortality data for colorectal cancer, for the period 1999 - 2014, were taken from the of the Institute of Public Health of Serbia " Dr Milan Jovanovic - Batut". Joinpoint regression analysis was used to estimate annual percent changes (APCs) in mortality and to identify critical stages in time where significant changes in trend occurred. Results: In central Serbia, in the period between 1999 and 2014, colorectal cancer was the second most common cause of mortality in both men and women. The average standardized mortality rate was 18.2 in men (per 100,000) and 10.5 in women (per 100,000). Rates were 1.7 times higher in men, with a remarkable annual increase of colorectal cancer mortality rate of 1.3% in the period 1999-2014, while in women the mortality rates were steady. In men, a significant increase in mortality rates was present in colon (APC 1.8%) as well as in rectosigmoidal junction cancer (APC 3.3%). Rise of 1.7% was present in colon carcinoma in men 35-74 years of age as well as an increase both in men and women 75 years of age and older in the period 1999-2014. Conclusion: Findings of present study revealed increasing mortality rates of colorectal cancer in Serbia. The implementation of nationally organized screening programmes is of paramount importance and should be conducted with higher efficacy in Serbia. Primary prevention measures should mainly focus on maintaining healthy body weight and a balanced diet as well as smoking and alcohol cessation. |
| Databáze: | OpenAIRE |
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