Susceptibilities of bacterial isolates from patients with cancer to levofloxacin and other quinolones
| Autor: | Dah Hsi Ho, Barbara LeBlanc, G. P. Bodey, Kenneth V. I. Rolston, N. Dholakia |
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| Rok vydání: | 1994 |
| Předmět: |
Ofloxacin
Gram-positive bacteria Levofloxacin Microbial Sensitivity Tests Biology Gram-Positive Bacteria medicine.disease_cause Microbiology Anti-Infective Agents Ciprofloxacin Neoplasms Gram-Negative Bacteria medicine Humans Pharmacology (medical) Antibacterial agent Pharmacology Bacteria Pseudomonas aeruginosa Stereoisomerism Bacterial Infections biochemical phenomena metabolism and nutrition bacterial infections and mycoses biology.organism_classification Infectious Diseases Staphylococcus aureus Antibacterial activity Research Article medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 38:848-852 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.38.4.848 |
| Popis: | The antibacterial activity of levofloxacin was compared with those of ofloxacin and ciprofloxacin against bacterial isolates from patients with cancer. In general, levofloxacin was as active or was twofold more active than ofloxacin and was two- to fourfold less active than ciprofloxacin against most gram-negative pathogens. Against Pseudomonas aeruginosa, ciprofloxacin was the most active agent tested (MIC for 90% of isolates tested, 1.0 microgram/ml). Overall, all three agents had similar activities against gram-positive organisms and were moderately active against methicillin-susceptible Staphylococcus aureus and coagulase-negative staphylococci, Streptococcus species, and Enterococcus species. |
| Databáze: | OpenAIRE |
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