Performance of the PSI and CURB-65 scoring systems in predicting 30-day mortality in healthcare-associated pneumonia
| Autor: | Liliana Zamora-Pérez, Alfredo Medina-González, Benjamín Trujillo-Hernández, Andrés Vázquez-Yáñez, José Guzmán-Esquivel, Efrén Murillo-Zamora |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Pneumonia severity index Youden's J statistic Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Healthcare associated Internal medicine medicine Humans 030212 general & internal medicine Mexico Aged Retrospective Studies Aged 80 and over business.industry Mortality rate Healthcare-Associated Pneumonia Middle Aged medicine.disease CURB-65 Pneumonia Cross-Sectional Studies Blood pressure 030228 respiratory system 30 day mortality Female business |
| Zdroj: | Medicina Clínica (English Edition). 150:99-103 |
| ISSN: | 2387-0206 |
| Popis: | Introduction Healthcare-associated pneumonia (HCAP) is the leading cause of infection in a hospital setting and is associated with a high mortality rate. This study aimed to evaluate the performance of the pneumonia severity index (PSI) and confusion, urea, respiratory rate, blood pressure, age≥65 (CURB-65) systems in predicting 30-day mortality in HCAP in adult patients. Patients and methods A cross-sectional study took place and data from 109 non-immunocompromised individuals aged>18 years were analyzed. The clinical diagnosis of HCAP included the presence of radiographic infiltrates in patients≥48hours after hospital admission. The PSI and CURB-65 scores were calculated and performance measures were estimated. Summary statistics were used to describe the study sample. The PSI and CURB-65 scores were calculated based on 20 and 5 criteria, respectively, and the performance indicators of the screening tools were estimated. Results The overall 30-day mortality was 59.6%. At every given threshold, PSI sensitivity was higher, but showed a lower specificity than the CURB-65, and the highest Youden index (0.392) was observed at cut-off V in the PSI. The area under the ROC curve was 0.737 (95% CI: 0.646-0.827) and 0.698 (95% CI: 0.600-0.797) using the PSI and CURB-65 systems, respectively (P=.323). Conclusion Our findings suggest that the performance of the PSI and CURB-65 is reasonable for predicting 30-day mortality in adult HCAP patients and may be used in healthcare settings. |
| Databáze: | OpenAIRE |
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