Different clinical effect of several types of airborne allergens on the severity of bronchial hyperreactivity
| Autor: | Katarína Perečinská, Slavomír Perečinský, Ondrej Ragač, Marek Varga, Andrea Jančová, Jozefína Petrovičová, Lenka Murínová, Tomáš Bačinský, L’ubomír Legáth |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Slovakia Adolescent medicine.disease_cause Bronchial Provocation Tests Airborne allergen Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine immune system diseases Forced Expiratory Volume Pollen Odds Ratio otorhinolaryngologic diseases medicine Humans Sensitization Bronchial hyperreactivity Asthma Air Pollutants business.industry General Medicine Odds ratio Allergens Middle Aged respiratory system medicine.disease respiratory tract diseases 030104 developmental biology medicine.anatomical_structure 030228 respiratory system chemistry Bronchial hyperresponsiveness Immunology Female Bronchial Hyperreactivity business Histamine |
| Zdroj: | Wiener klinische Wochenschrift. 129:674-679 |
| ISSN: | 1613-7671 0043-5325 |
| DOI: | 10.1007/s00508-017-1220-0 |
| Popis: | Atopic sensitization belongs to the most common risk factors for bronchial asthma. However, in clinical practice, it is not clear whether sensitization against pollen and perennial allergens is differently associated with the severity of bronchial hyperresponsiveness (BHR). To find out whether patients sensitized to perennial allergens differ in severity of bronchial hyperresponsiveness from patients sensitized to pollen allergens. The study includes 109 patients. Based on the results of skin prick tests, patients were divided into three groups: sensitivity to pollen allergens – group A; sensitivity to perennial allergens – group B; sensitivity to both pollen and perennial allergens – group C. Based on the histamine bronchoprovocation test, we compared the values of histamine provocative concentration causing a 20% drop in FEV1 (PC20) among particular groups of patients. Mild bronchial hyperresponsiveness was determined if the value of PC20 was >4 mg/ml, while if the value of PC20 was |
| Databáze: | OpenAIRE |
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