Attenuation-corrected vs. nonattenuation-corrected 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography in oncology
| Autor: | Ingrid I. Riphagen, Otto S. Hoekstra, U. Joshi, Arthur van Lingen, Gerrit J. J. Teule, Pieter G. Raijmakers |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Cancer Research
medicine.medical_specialty Positron emission tomography Attenuation correction Diagnostic accuracy Tomography emission-computed (MeSH) Sensitivity and Specificity Fluorodeoxyglucose F18 Neoplasms medicine Humans Radiology Nuclear Medicine and imaging Neoplasms (MeSH) Systematic review (MeSH) Medicine(all) medicine.diagnostic_test business.industry Attenuation Human (MeSH) Oncology Positron-Emission Tomography Radiology Tomography Tomography X-ray computed (MeSH) Radiopharmaceuticals Nuclear medicine business Correction for attenuation Research Article Deoxyglucose (MeSH) |
| Zdroj: | Molecular Imaging and Biology Joshi, U, Raijmakers, P G H M, Riphagen, I I, Teule, G J J, van Lingen, A & Hoekstra, O S 2007, ' Attenuation-corrected vs. nonattenuation-corrected 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography in oncology : a systematic review ', Molecular Imaging and Biology, vol. 9, no. 3, pp. 99-105 . https://doi.org/10.1007/s11307-007-0076-5 |
| ISSN: | 1536-1632 |
| Popis: | PURPOSE: To perform a systematic review and meta-analysis to determine the diagnostic accuracy of attenuation-corrected (AC) vs. nonattenuation-corrected (NAC) 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography (FDG-PET) in oncological patients.PROCEDURES: Following a comprehensive search of the literature, two reviewers independently assessed the methodological quality of eligible studies. The diagnostic value of AC was studied through its sensitivity/specificity compared to histology, and by comparing the relative lesion detection rate reported with NAC-PET vs. AC, for full-ring and dual-head coincidence PET (FR- and DH-PET, respectively).RESULTS: Twelve studies were included. For FR-PET, the pooled sensitivity/specificity on a patient basis was 64/97% for AC and 62/99% for NAC, respectively. Pooled lesion detection with NAC vs. AC was 98% [95% confidence interval (95% CI): 96-99%, n = 1,012 lesions] for FR-PET, and 88% (95% CI:81-94%, n = 288 lesions) for DH-PET.CONCLUSIONS: Findings suggest similar sensitivity/specificity and lesion detection for NAC vs. AC FR-PET and significantly higher lesion detection for NAC vs. AC DH-PET. |
| Databáze: | OpenAIRE |
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